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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T60535 | PPARα/γ agonist 1 | ||
PPARα/γ agonist 1 is a potent and dual PPARα/γ partial agonist which is a promising prototype for the research of dyslipidemia and diabetes. PPARα/γ agonist 1 has EC50 values of 28 nM and 69 nM for PPARα and PPARγ, respe... | |||
T6524 | GW0742 | GW610742 | PPAR |
GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ). | |||
T21812 | LT175 | ||
LT175, a dual PPARα/γ ligand, demonstrates potent insulin-sensitizing effects while exhibiting reduced adipogenic properties. This compound is an orally active partial agonist targeting PPARγ, with EC50 values of 0.22 μm... | |||
T35800 | MD001 | ||
MD001 is a dual agonist of peroxisome proliferator-activated receptor α (PPARα) and PPARγ.1 It binds to PPARα and PPARγ (Kds = 9.55 and 0.14 μM, respectively) but does not bind to PPARβ/δ at concentrations up to 500 μM. ... | |||
T14216 | AMG 837 | Others | |
AMG 837 is a partial GPR40 agonist with an EC50 value of 13 nM, showcasing 85% of the maximal activity displayed by DHA in standard assay conditions, indicating its high potency and selectivity in vitro. This compound ex... | |||
T83765 | Dendrogenin A | DDA | |
Dendrogenin A (DDA) is a compound acting as a selective liver X receptor (LXR) modulator, cholesterol epoxide hydrolase inhibitor (Ki = 120 nM), and a metabolic product of cholesterol, originating from 5,6α-epoxy cholest... |